Genetic Cancer Ovary

Cancer of the ovary.

Ovarian cancer is not only the commonest but also the most lethal gynaecological malignancy, partly because the majority of patients present with advanced disease. Nevertheless, the management of patients with ovarian neoplasms has changed substantially recently, with improved survival due to better screening strategies, major advances in chemotherapy and the constantly evolving role of surgery...

Investigation of genetic factors associated with polycystic ovary syndrome

Introduction: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders and causes 75% of infertility due to ovulation disorders in reproductive age. Women with PCOS have oligomenorrhea and hyperandrogenism that affect their quality of life and fertility at the same time. This syndrome has been one of the most controversial endocrine issues for many years. Research today su...

GENETIC AND NON-GENETIC THEORIES ON THE ETIOLOGY OF POLYCYSTIC OVARY SYNDROME: A REVIEW

The genetic basis of polycystic ovary syndrome.

Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age. The disorder is characterized by clinical features of hyperandrogenism, menstrual irregularities and often central obesity and hyperinsulinaemia. PCOS may increase the risk for infertility, type 2 diabetes mellitus, dyslipidaemia, cardiovascular disease and endometrial cancer, emphasizing the need for ...

Hereditary portion as an initial genetic approach in gynecologic cancer: synchronous tumor of ovary and endometrium

To the editor: Hereditary portion and genetic status are very important to work out strategies for cancer prevention and early detection in gynecologic cancers. Familial history of related cancers within the second degree relatives are approximately 10% and 20% in endometrial cancer and ovarian cancer, respectively [1,2]. The proportion of genetic background and germline mutation in Korean wome...